Humpath.com - Human pathology

Most recent articles

• splenic diseases

  6 June

  PO
  See also : splenic anomalies

• peptide-vesicle system

  3 June

  References
  Molecular Evolution in a Peptide-Vesicle System. Mayer C, Schreiber U, Dávila MJ, Schmitz OJ, Bronja A, Meyer M, Klein J, Meckelmann SW. Life (Basel). 2018 May 24;8(2). pii: E16. doi:10.3390/life8020016. PMID: #29795023#

• molecular evolution

  3 June

  WKP
  Definition : Molecular evolution is the process of change in the sequence composition of cellular molecules such as DNA, RNA, and proteins across generations.
  The field of molecular evolution uses principles of evolutionary biology and population genetics to explain patterns in these changes.
  Major topics in molecular evolution concern the rates and impacts of single nucleotide changes, neutral evolution vs. natural selection, origins of new genes, the genetic nature of complex (...)

• mucin producing tumors

  30 May

• mucin producing mammary carcinomas

  30 May

  Types
  columnar cell mucinous carcinoma
  cystadenocarcinoma
  ductal carcinoma NOS with focal mucin production
  lobular carcinoma (rarely, Pathol Int 2009;59:405)
  metastatic tumors, include GI and chordoma (APMIS 2006;114:726)
  mucinous carcinoma / colloid carcinoma
  mucinous cystadenocarcinoma
  mucoepidermoid carcinoma
  neuroendocrine carcinoma (Am J Surg Pathol 1991;15:677)
  signet ring carcinoma
  See also
  mucin producing tumors
  mammary (...)

• flat urothelial dysplasia

  23 May

  Images
  Webpathology
  http://www.webpathology.com/image.asp?n=5&Case=57
  Types
  low grade
  simple flat urothelial dysplasia / / low-grade flat urothelial dysplasia
  The urothelial lining is somewhat thickened consisting of 8 to 10 layers of cells.
  There is loss of polarity with minimal nuclear pleomorphism, nuclear enlargement and hyperchromasia.
  Mitotic activity is not increased.
  There is no inflammation to account for these cytologic changes.
  The degree of atypia is not (...)

• placental calcifications

  17 May

  placental calcification
  See also
  placental anomalies
  calcifications

• mammary carcinoma with medullary features

  14 May

  Carcinoma with medullary features (CMF) of the breast
  |PO|
  Definition: Carcinoma with medullary features (CMF) includes :
  mammary medullary carcinoma
  atypical medullary carcinoma
  invasive carcinoma, no special type (NST) with features of pushing borders, syncytial growth, high grade nuclei and prominent lymphoid infiltrate.
  WHO Classification of Tumors of the Breast (2013) recommends using the term Carcinoma with medullary features (CMF) rather than medullary carcinoma or (...)

• KL

  14 May

  Klotho WKP
  Definition: Klotho is an enzyme that in humans is encoded by the KL gene.
  The KL gene encodes a type-I membrane protein that is related to β-glucuronidases.
  Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF.
  Also, mutations within the KL protein have been associated with ageing, bone (...)

• anal pathology

  8 May

  Pathology : anal pathology
  anal malformations
  anal anomalies
  anal lesional syndromes
  anal diseases
  anal tumors
  congenital defects
  Infectious diseases
  Inflammatory diseases Crohn disease fissure fistula granuloma inguinale HIV lymphogranuloma venereum lymphoid polyp syphilis ulcer ulcerative colitis
  Benign anomalies / non-neoplastic lesions granular cell tumor hemorrhoids hypertrophic HSV hypertrophied papillae Hirschsprung inflammatory cloacogenic polyp internal anal (...)

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