Humpath.com - Human pathology

Most recent articles

• IUN-3-CK20/CD44s/p53 cocktail

  2 December

  Triple Antibody Cocktail Intraurothelial Neoplasm-3 (IUN-3-CK20/CD44s/p53)
  Reference
  Utility of a Triple Antibody Cocktail Intraurothelial Neoplasm-3 (IUN-3-CK20/CD44s/p53) and α-Methylacyl-CoA Racemase (AMACR) in the Distinction of Urothelial Carcinoma In Situ (CIS) and Reactive Urothelial Atypia. Aron M, Luthringer DJ, McKenney JK, Hansel DE, Westfall DE, Parakh R, Mohanty SK, Balzer B, Amin MB. Am J Surg Pathol. 2013 Dec;37(12):1815-23. doi:10.1097/PAS.0000000000000114 .PMID: (...)

• AMY1A

  2 December

  Immunochemistry
  Amylase α-1A (AMY1A) differentiate Chromophobe Renal Cell Carcinoma from Benign Oncocytoma. (#24225843#) Chromophobe renal cell carcinoma (ChRCC) and oncocytoma present with a perplexing overlap of morphologic and immunohistochemical features. ChRCC have deletions in the 1p21.1 region including the amylase α-1A gene (AMY1A). No such deletions are found in oncocytoma. Instead, oncocytomas shared other deletions on chromosome 1: 1p31.3, 1q25.2, and 1q44. AMY1A can be of (...)

• discontinuous foci of cancer in prostatic biopsy

  2 December

  References
  Discontinuous Foci of Cancer in a Single Core of Prostatic Biopsy: When it Occurs and Performance of Quantification Methods in a Private-practice Setting. Schultz L, Maluf CE, da Silva RC, Falashi Rde H, da Costa MV, Schultz MI. Am J Surg Pathol. 2013 Dec;37(12):1831-6. doi:10.1097/PAS.0000000000000112 .PMID: #24225844#

• Rare tumoral cells in CSF

  29 November

  References
  Development of a new method for identification and quantification in cerebrospinal fluid of malignant cells from breast carcinoma leptomeningeal metastasis. Le Rhun E, Massin F, Tu Q, Bonneterre J, Bittencourt Mde C, Faure GC. BMC Clin Pathol. 2012 Nov 12;12:21. doi:10.1186/1472-6890-12-21. PMID: #23145812# [Free]

• circulating tumor cells in lung cancer

  29 November

  References
  Circulating tumor cells in lung cancer. Young R, Pailler E, Billiot F, Drusch F, Barthelemy A, Oulhen M, Besse B, Soria JC, Farace F, Vielh P. Acta Cytol. 2012;56(6):655-60. doi:10.1159/000345182 . PMID: #23207444#

• Circulating tumor cells in prostate cancer

  29 November

  Open references
  mRNA-Seq of single prostate cancer circulating tumor cells reveals recapitulation of gene expression and pathways found in prostate cancer. Cann GM, Gulzar ZG, Cooper S, Li R, Luo S, Tat M, Stuart S, Schroth G, Srinivas S, Ronaghi M, Brooks JD, Talasaz AH. PLoS One. 2012;7(11):e49144. doi:10.1371/journal.pone.0049144 . PMID: #23145101# [Free]
  References
  Detection of circulating tumor cells in different stages of prostate cancer. Thalgott M, Rack B, Maurer T, (...)

• Circulating tumor cells in pancreatic cancer

  29 November

  References
  Circulating tumor cells in pancreatic cancer patients: methods of detection and clinical implications. Tjensvoll K, Nordgård O, Smaaland R. Int J Cancer. 2014 Jan 1;134(1):1-8. doi: 10.1002/ijc.28134. PMID: #23447365#

• isolation of circulating tumor cells by immunomagnetic enrichment and fluorescence-activated cell sorting

  29 November

  Isolation of circulating tumor cells by immunomagnetic enrichment and fluorescence-activated cell sorting (IE/FACS)
  References
  Isolation of circulating tumor cells by immunomagnetic enrichment and fluorescence-activated cell sorting (IE/FACS) for molecular profiling. Magbanua MJ, Park JW. Methods. 2013 Jul 26. doi:S1046-2023(13)00278-8. 10.1016/j.ymeth.2013.07.029 . PMID: (...)

• Neuroendocrine Differentiation in Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor

  17 October

  Neuroendocrine Differentiation in Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor. Small cell lung cancer (SCLC) transformation during epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) treatment in lung cancer
  Small cell lung cancer (SCLC) transformation during epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) treatment in lung cancer has been suggested as one of possible resistance mechanisms.
  Open references (...)

• synovial chondromatosis

  15 October

  synovial osteochondromatosis, primary synovial osteochondromatosis, synovial chondrometaplasia; Reichel’s syndrome or Reichel-Jones-Henderson syndrome, named after Friedrich Paul Reichel, Hugh Toland Jones and Melvin Starkey Henderson. WP
  Definition: Synovial chondromatosis is a disease affecting the synovium, a thin flexible membrane around a joint.

previous page | next page