Humpath.com - Human pathology

Most recent articles

• hyaline bodies

  29 October

  Examples
  Rushton bodies

• Myocarditis Associated With Immune Checkpoint Inhibitor Therapy

  28 October

  Myocarditis Associated With Immune Checkpoint Inhibitor Therapy
  Synopsis
  significant and prominent interstitial inflammatory infiltrate composed of numerous histiocytes with interspersed lymphocytes.
  This lymphohistiocytic infiltrate was associated with evidence of myocardial injury. This included loss of myocyte nuclei, myocytes with irregular cell membranes with moth-eaten appearance, hypereosinophilia, and shrunken and irregular cardiac myocytes, but not associated with fibrosis . (...)

• PRKDs

  28 October

  Definition : Serine/threonine-protein kinase Ds are enzymes that in humans is encoded by the PRKDs genes.
  Members of the protein kinase D ( PKDs ) family function in many extracellular receptor-mediated signal transduction pathways.
  Pathology
  polymorphous adenocarcinoma of the salivary gland harbor genetic alterations affecting PRKD genes. PMID: #31492931#
  The PRKD1 E710D hotspot mutation is highly specific in separating polymorphous adenocarcinoma of the palate from adenoid cystic (...)

• PRKD1

  28 October

  WKP
  Definition : Serine/threonine-protein kinase D1 is an enzyme that in humans is encoded by the PRKD1 gene.
  Members of the protein kinase D ( PKDs ) family function in many extracellular receptor-mediated signal transduction pathways.
  ThePRKD1 / PRKCM gene encodes a cytosolic serine-threonine kinase that binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface.
  Pathology
  polymorphous adenocarcinoma of the (...)

• myoepithelial cells with admixed ducts

  28 October

  Dark angulated myoep cells w admixed ducts (arrow)
  Synopsis
  Dark angulated myoepithelial cells w admixed ducts > adenoid cystic carcinoma : https://twitter.com/dannyjlubinpath/status/1303871218303602689

• open chromatin

  28 October

  decondensed chromatin
  Examples
  https://twitter.com/dannyjlubinpath/status/1303871218303602689
  See also
  chromatin chromatin appearance

• MUC3

  28 October

  ( MUC3A and MUC3B ) PO
  See also
  MUCs

• mucins

  28 October

  mucin WKP PO
  Definition : Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by epithelial tissues in most animals.
  Mucins’ key characteristic is their ability to form gels; therefore they are a key component in most gel-like secretions, serving functions from lubrication to cell signalling to forming chemical barriers.
  They often take an inhibitory role.
  Some mucins are associated with controlling mineralization, including nacre (...)

• memory B cells

  28 October

• lipomatous hamartoma

  27 October

  Pathology
  lipomatous hamartomas / lipomatous hamartoma nevus lipomatosus superficialis
  See also
  cutaneous hamartomas

previous page | next page