Peck, M., Moffat, D., Latham, B., Badrick, T., Review of diagnostic error in anatomical pathology and the role and value of second opinions in error preventions, J. Clin. Pathol. 71 (11) (2018) 995-1000.
The aim of the humpath.com project is to constuct an ontology in human pathology, the study of anomalies and diseases in humans.
For more information, see : http://www.humpath.com/spip.php?article1
Most recent articles
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diagnostic errors
7 March -
prediction of tumor type
7 MarchPaywall references
Massard C, Loriot Y, Fizazi K. Carcinomas of an unknown primary origin–diagnosis and treatment. Nat Rev Clin Oncol. 2011 Nov 1;8(12):701-10. doi: 10.1038/nrclinonc.2011.158. PMID: 22048624
Abraham, J., Spetzler, D., et al. (2021) Machine learning analysis using 77,044 genomic and transcriptomic profiles to accurately predict tumor type. Translational Oncology, 14(3) 101016. https://doi.org/10.1016/j.tranon.2021.101016
Peck, M., Moffat, D., Latham, B., Badrick, T., (...) -
theca
3 Marchtheca of follicle ; theca folliculi ; follicular theca WKP
Definition : The theca folliculi comprise a layer of the ovarian follicles. They appear as the follicles become secondary follicles.
The theca are divided into two layers, the theca interna and the theca externa.
Theca cells are a group of endocrine cells in the ovary made up of connective tissue surrounding the follicle. They have many diverse functions, including (...) -
theca externa
3 MarchWKP
Definition : The theca externa is the outer layer of the theca folliculi. It is derived from connective tissue, the cells resembling fibroblasts, and contains abundant collagen.
During ovulation, the surge in luteinizing hormone increases cAMP which increases progesterone and PGF2α production. The PGF2α induces the contraction of the smooth muscle cells of the theca externa, increasing intrafollicular pressure.
This aids in rupture of the mature oocyte, or immature oocyte at the (...) -
theca interna
3 MarchWKP
Definition : Theca lutein cells are also known as small luteal cells.
Theca interna cells express receptors for luteinizing hormone (LH) to produce androstenedione, which via a few steps, gives the granulosa the precursor for estrogen manufacturing.
After rupture of the mature ovarian follicle, the theca interna cells differentiate into the theca lutein cells of the corpus luteum. Theca lutein cells secrete androgens and (...) -
Schneiderian papilloma
28 FebruaryDefinition : Schneiderian papillomas are benign neoplasms that are associated with three key characteristics: tendency to recur, capacity for local destruction, and association with squamous cell carcinoma.
They are classified into inverting, fungiform, and oncocytic varieties. The inverting and fungiform varieties are the most common, and the inverting variety has the highest rate of association with malignancy.
The inverting and oncocytic varieties are classically found on the lateral (...) -
carcinosarcoma with a chondrosarcomatous component
27 FebruaryOpen references
Carcinosarcoma of the Gallbladder with Chondrosarcomatous Differentiation.
https://pubmed.ncbi.nlm.nih.gov/30881717/
Synchronous carcinosarcoma of the lower ureter and renal pelvis with heterologous chondrosarcomatous elements
https://pubmed.ncbi.nlm.nih.gov/26458704/
Paywall references
So-called carcinosarcoma of the duodenum with a chondrosarcomatous component.
https://pubmed.ncbi.nlm.nih.gov/26249526/
Sarcomatoid urothelial carcinoma with chondrosarcomatous (...) -
carcinosarcoma
27 FebruaryDefinition : Carcinosarcoma is a biphasic malignant tumor consisting of both carcinomatous and sarcomatous components,
Subtypes
carcinosarcoma with a chondrosarcomatous component -
CDSS
27 FebruaryClinical Decision Support System (CDSS)
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solitary necrotic nodule of the liver
21 Februaryhepatic solitary necrotic nodule PO
See also
hepatic necrotic nodule
Open references
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415885/
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