Humpath.com - Human pathology

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• spironolactone bodies

  21 September

  spironolactone body
  Images
  Conn syndrome: aldosterone secreting adrenal cortical adenoma, note spironolactone bodies https://twitter.com/AssaadAM/status/715046004542869504
  See also
  spironolactone
  bodies

• Conn syndrome

  21 September

  Images
  Conn syndrome: aldosterone secreting adrenal cortical adenoma, note spironolactone bodies https://twitter.com/AssaadAM/status/715046004542869504
  See also
  clinical syndromes

• giant condyloma acuminatum

  21 September

  Giant condyloma acuminatum (Buschke-Löwenstein tumor)
  Images
  Giant condyloma acuminatum https://twitter.com/DanglisFotiosMD/status/778508686742478848
  See also
  condyloma acuminatum

• CD24

  21 September

  Pathology
  CD24 was shown to be overexpressed in high-grade serous carcinoma (HGSC) effusions compared to malignant mesothelioma (MM) in gene expression array analysis.
  CD24 is highly useful in differentiating high-grade serous carcinoma from benign and malignant mesothelial cells. http://dx.doi.org/10.1016/j.humpath.2016.08.005 In a study, Reactive mesothelial cells were CD24-negative in all carcinoma specimens. The overexpression of CD24 in ovarian carcinoma effusions compared to (...)

• prostate cancer grading

  21 September

  Examples
  Gleason grading system
  2016 Epstein et al. grading system (#26166626#)
  References
  A Contemporary Prostate Cancer Grading System: A Validated Alternative to the Gleason Score. Epstein JI, Zelefsky MJ, Sjoberg DD, Nelson JB, Egevad L, Magi-Galluzzi C, Vickers AJ, Parwani AV, Reuter VE, Fine SW, Eastham JA, Wiklund P, Han M, Reddy CA, Ciezki JP, Nyberg T, Klein EA. Eur Urol. 2016 Mar;69(3):428-35.
  doi:10.1016/j.eururo.2015.06.046 .
  PMID: (...)

• anomalies of the jaws

  21 September

  Examples
  cystic anomalies of the jaws
  See also
  pathology of the jaws

• pathology of the jaws

  21 September

  PO
  Localization
  temporomandibular joint pain-dysfunction syndrome
  Pathology
  hypoplasia
  hyperplasia
  inflammation osteomyelitis acute suppurative osteomyelitis alveolar osteitis chronic recurrent multifocal osteomyelitis (CRMO) condensing osteitis diffuse sclerosing osteitis medication related osteonecrosis (MRONJ) osteoradionecrosis (ORN) SAPHO syndrome secondary chronic osteomyelitis central giant cell granuloma dental granuloma hyaline ring like structures (...)

• anal basaloid squamous cell carcinoma

  20 September

  Basaloid Squamous Cell Carcinoma of the Anus; Basaloid SCC of the Anus
  Definition: Basaloid squamous cell carcinoma (SCC) of the anus, previously called cloacogenic carcinoma, is a subtype of SCC. Basaloid SCC of the anus is characterized by 4 major histologic patterns and is consistently HPV driven.
  References
  Basaloid Squamous Cell Carcinoma of the Anus Revisited.
  Graham RP, Arnold CA, Naini BV, Lam-Himlin DM.
  Am J Surg Pathol. 2016 Mar;40(3):354-60. doi: (...)

• solitary cervical cystic anomalies

  20 September

  solitary cervical cystic lesions; cystic neck lesions.
  The most-common variety of solitary cervical cystic lesion is the branchial cleft cyst (BCC), which can become malignant.
  According to the strict diagnostic criteria for branchial cleft cystic carcinoma (BCCC), proposed by Martin et al. and modified by Khafif et al., fewer than 40 cases have been reported.
  The majority of previously suspected BCCCs were actually metastatic cystic lymph nodes; misdiagnosis can occur due to the (...)

• branchial cleft cyst carcinoma

  20 September

  carcinoma arising in a branchial cyst.
  Definition: squamous cell carcinoma arising in a branchial cleft cyst .
  BCCC is currently regarded as an uncommon clinicopathological entity.
  In 1950, Martin et al. reviewed 250 cases of BCCC, of which the majority represented metastatic head and neck primary cancers resulting from an absence of long-term follow-up.
  Strict diagnostic criteria for BCCC were subsequently established, as follows:
  a) tumor located along the anterior border of the (...)

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