Humpath.com - Human pathology

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• eccentric nuclei

  9 February

  eccentric nucleus
  Examples
  eccentric nuclei / eccentric nucleus rhabdoid inclusions in clear cell renal cell carcinoma / clear cell RCC https://twitter.com/MoravekMD/status/1093981605738225664
  See also
  nuclear anomalies nuclear position anomalies

• nuclear position anomalies

  9 February, by admin

  Examples
  eccentric nuclei / eccentric nucleus rhabdoid inclusions in clear cell renal cell carcinoma / clear cell RCC https://twitter.com/MoravekMD/status/1093981605738225664
  See also
  nuclear anomalies

• myxedematous stroma

  9 February

  Examples
  Proliferative fasciitis https://twitter.com/histiocytosisX/status/726137886693806081 https://twitter.com/VishwasParekh/status/701774294997716992 https://twitter.com/feaselp811/status/733792267266330624
  See also
  tumoral stroma myxoid stroma edematous stroma

• hepatic helminthiasis

  9 February

  Examples
  Fasciola sp. or Schistomia sp. https://twitter.com/hematogones/status/1093990804484440064

• cutaneous blastomycosis

  9 February

  Images
  Cutaneous North American blastomycosis https://twitter.com/jessicaghaferi/status/939205412250931200
  See also
  cutaneous infections
  blastomycosis north american blastomycosis

• central zone

  9 February

  CZ
  Definition : CZ surrounds the ejaculatory ducts. The central zone accounts for roughly 2.5% of prostate cancers; these cancers tend to be more aggressive and more likely to invade the seminal vesicles.
  Glands of central zone at the base of the prostate can mimic high-grade PIN architecturally.
  There is nuclear crowding and pseudostratification with tufted, papillary and even cribriform areas within the glands.
  Central zone glands may sometimes be seen at the end of a prostate biopsy (...)

• eosinophilic granulomatosis with polyangiitis

  9 February

  EGPA ; Churg-Staruss syndrome
  |WKP|
  Definition : Eosinophilic granulomatosis with polyangiitis (EGPA), also known as Churg–Strauss syndrome (CSS) or allergic granulomatosis, is an extremely rare autoimmune condition that causes inflammation of small and medium-sized blood vessels (vasculitis ) in persons with a history of airway allergic hypersensitivity (atopy ).
  Images
  Eosinophilic granulomatosis with polyangiitis (EGPA), former Churg-Staruss syndrome. (...)

• tumoral cell cytoplasm

  9 February

  cytoplasm of tumoral cells
  Examples
  cytoplasmic clearing / clear cytoplasm SDH-mutated paraganglioma https://twitter.com/CaDxPath/status/1094046992827703296 SDHmut paragangliomas show distinctive morphology : very round nests, epithelioid cells, some cytoplasmic clearing.
  See also
  cytoplasm appearance

• nested architecture

  9 February

  tumoral nests
  Examples
  SDH-mutated paraganglioma https://twitter.com/CaDxPath/status/1094046992827703296 SDHmut paragangliomas show distinctive morphology : very round nests, epithelioid cells, some cytoplasmic clearing.

• SDH-mutated paraganglioma

  9 February

  Images : SDH-mutated paraganglioma https://twitter.com/CaDxPath/status/1094046992827703296 SDHmut paragangliomas show distinctive morphology : very round nests, epithelioid cells, some cytoplasmic clearing.
  Genetics
  Germline mutations in three of the succinate dehydrogenase (SDH, mitochondrial complex II) subunits (SDHD, SDHB and SDHC) cause susceptibility to head and neck paragangliomas, and may be found in approximately 20% of unselected patients.
  In addition, germline SDHD and (...)

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