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Tuesday 27 February 2007

Follicle-stimulating hormone enables ovarian folliculogenesis to the antral follicle stage and is essential for Sertoli cell proliferation and maintenance of sperm quality in the testis.

Members of the pituitary glycoprotein hormone family, of which FSH is one (see also luteinizing hormone, MIM.152780; chorionic gonadotropin, MIM.118860; and thyroid-stimulating hormone, MIM.188540) consist of a shared alpha chain (MIM.118850) and a beta chain encoded by a separate gene.

The FSHB gene encodes the beta subunit of follicle-stimulating hormone.


- Prior JC. FSH and bone—important physiology or not? Trends Mol Med. 2007 Jan;13(1):1-3. PMID: 17141571