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right atrial isomerism

Thursday 22 March 2007

Definition: Isomerism of the right atrial appendages is caracterized by bilateral morphologically right atrial appendages with mirror-imaged of cardiac atria. It is associated with complex congenital cardiac lesions and ciliary abnormalities.


- complex cardiac malformations

  • anomalies of pulmonary venous return +/- pulmonary venous obstruction

- asplenia
- bronchial ciliary anomalies

  • narrow, disorganized bronchial epithelium
  • abundant goblet cells
  • short, angulated cilia with a random orientation
  • abnormal central microtubule doublet

See also

- isomerisms

  • cardiac isomerism
  • pulmonary isomerism
  • visceral isomerism

- primary ciliary dyskinesia (PCD) and ciliary anomalies

- random lateralization

  • mirror-imaged arrangement of the organs
  • isomeric patterns

- polysplenia or asplenia
- bronchial isomerisms

  • left bronchial isomerism
  • right bronchial isomerism

- visceroatrial situs inversus


- Raman R, Al-Ali SY, Poole CA, Dawson BV, Carman JB, Calder L. Isomerism of the right atrial appendages: clinical, anatomical, and microscopic study of a long-surviving case with asplenia and ciliary abnormalities. Clin Anat. 2003 May;16(3):269-76. PMID: 12673825