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prostatic transition zone

Monday 21 July 2008

Transition zone represents 5% of prostatic volume and is formed by 2 pear shaped lobes surrounding proximal urethra. It contains moderately compact fascicles of smooth muscle.

Pathology

It is the preferential site of nodular prostatic hyperplasia and may expand to bulk of gland.

It is the site of 10% of prostate cancers (preferentially large duct carcinomas).

Tumors

Morphologic spectrum of prostatic glands of variable size with tall columnar cells displaying basally oriented nuclei and clear to pale pink cytoplasm (TZ-LOOK) is characteristic of the well to moderately differentiated component of transition zone (TZ) tumors. (18769336)

See also

- Prostate
- prostatic transition zone tumors

References

- Garcia JJ, Al-Ahmadie HA, Gopalan A, Tickoo SK, Scardino PT, Reuter VE, Fine SW. Do Prostatic Transition Zone Tumors Have a Distinct Morphology? Am J Surg Pathol. 2008 Aug 30. PMID: 18769336