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premature aging diseases

Tuesday 28 October 2003

Classification

- Werner syndrome (MIM.277700)
- Bloom syndrome (MIM.210900)
- RECQL4 (MIM.603781) : mutations in the Rothmund-Thomson syndrome (MIM.268400)
- RECQL5 (MIM.603781)
- Progeria (mutations in lamin A/C)

References

- Razzaque MS, Lanske B. Hypervitaminosis D and premature aging: lessons learned from Fgf23 and Klotho mutant mice. Trends Mol Med. 2006 Jul;12(7):298-305. PMID: #16731043#

- Chang S. Modeling premature aging syndromes with the telomerase knockout mouse. Curr Mol Med. 2005 Mar;5(2):153-8. PMID: #15974868#

- Novelli G, D’Apice MR. The strange case of the "lumper" lamin A/C gene and human premature ageing. Trends Mol Med. 2003 Sep;9(9):370-5. PMID: #13129702#

- Bohr VA: Human premature aging syndromes and genomic instability. Mech Ageing Dev 123:987, 2002.