Friday 6 January 2017
Definition: Chemokine (C-C motif) ligand 21 (CCL21) is a small cytokine belonging to the CC chemokine family of chemokines.
CCL21 chemokine is also known as 6Ckine (because it has six conserved cysteine residues instead of the four cysteines typical to chemokines), exodus-2, and secondary lymphoid-tissue chemokine (SLC).
CXCL13 and CCL21 are expressed in ectopic lymphoid follicles in cutaneous lymphoproliferative disorders.
Ohmatsu H, Sugaya M, Kadono T, Tamaki K.
J Invest Dermatol. 2007 Oct;127(10):2466-8.
PMID: 17495955 Free