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carcinomas

Wednesday 12 November 2003

carcinoma

Classification

- adenocarcinomas

- squamous cell carcinomas
- urothelial carcinoma
- endocrine carcinomas
- renal cell carcinomas
- bronchioloalveolar carcinoma
- undifferentiated carcinomas / anaplastic carcinomas

Phenotypes

- small cell carcinomas
- marge cell carcinomas

Localizations

- head and neck carcinomas
- pulmonary carcinomas
- digestive carcinomas
- genital carcinomas
- urinary carcinomas

Etiology

- inactivation of tumor suppresor genes
- activation of oncogenes
- creation of fusion genes

  • translocation t(15;19)(q13;p13.1) creating BRD4/NUT gene in midline aggressive carcinoma (12543779)

See also

- tumoral classification / tumoral types
-  sarcomas

References

- Kumar-Sinha C, Tomlins SA, Chinnaiyan AM. Evidence of recurrent gene fusions in common epithelial tumors. Trends Mol Med. 2006 Nov;12(11):529-36. PMID: 17011825