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vulvar squamous lesions

Wednesday 1 September 2010

Examples

- simplex vulvar intraepithelial neoplasia
- vulvar intraepithelial neoplasia
- vulvar squamous cell carcinomas

Immunochemistry

- ProEx C is a useful proliferation marker for high-grade VIN analogous to the staining patterns reported in high-grade cervical intraepithelial neoplasia. (20697251)

References

- Immunohistochemical Patterns of ProEx C in Vulvar Squamous Lesions: Detection of Overexpression of MCM2 and TOP2A. Chen H, Gonzalez JL, Brennick JB, Liu M, Yan S. Am J Surg Pathol. 2010 Sep;34(9):1250-7. PMID: 20697251