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combined classical carcinoid and goblet cell carcinoid tumor

Monday 6 September 2010

Definition: Carcinoid tumors are the most common neoplasms of the appendix. Histologically they have been categorized as classical, tubular, or goblet cell types.

Goblet cell carcinoid has been regarded as a distinctive tumor type, not related to classic carcinoids. Combinations of these 2 tumor types have rarely been described. (20631606)

The occurrence of both carcinoid types in the same appendices suggests a closer histogenetic relationship than previously believed, although the possibility that the 2 components represent separate, independent primaries ("collision tumors") can also be considered.

See also

- goblet cell carcinoid tumor

References

- Combined classical carcinoid and goblet cell carcinoid tumor: a new morphologic variant of carcinoid tumor of the appendix. Chetty R, Klimstra DS, Henson DE, Albores-Saavedra J. Am J Surg Pathol. 2010 Aug;34(8):1163-7.PMID: 20631606