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chronic pancreatitis

Friday 14 November 2003

Etiology

- hereditary chronic pancreatitis (HCP)
- alcoholic chronic pancreatitis
- cystic fibrosis-associated chronic pancreatitis
- fibrocalculous pancreatic diabetes (FCPD)

Susceptibility

- SPINK1 variants
- KRT8 mutations (KRT8-associated chronic pancreatitis)

References

- Bhanot UK, Moller P, Hasel C. Dichotomy of fates of pancreatic epithelia in chronic pancreatitis: apoptosis versus survival. Trends Mol Med. 2006 Aug;12(8):351-7. PMID: 16828345

- Cavestro GM, Frulloni L, Nouvenne A, Neri TM, Calore B, Ferri B, Bovo P, Okolicsanyi L, Di Mario F, Cavallini G. Association of keratin 8 gene mutation with chronic pancreatitis. Dig Liver Dis. 2003 Jun;35(6):416-20. PMID: 12868678

- Drenth JP, Verlaan M. Genetic aspects of chronic pancreatitis, and the exploration of an association with keratin 8/18. Dig Liver Dis. 2003 Jun;35(6):386-8. PMID: 12868673