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intestinal segmental dilatation

Wednesday 20 April 2011

Segmental dilatation of intestine (SDI) is a rare disorder that leads to functional obstruction without stenosis and normally functioning ganglion cells. The etiology of the disease is unknown. Definitive treatment consists of segmental resection of the dilated segment with end-to-end anastomosis.

Ileal dysgenesis

"Ileal dysgenesis" describes the segmental dilatation of the terminal ileum treated in seven patients presenting from birth to 15 yr. Manifestations include saccular segmental ileal dilatation adherent to the peritoneal surface of an omphalocele sac in two neonates, a radiographically delineated enterolith in a child studied for an unrelated disorder, and a syndrome including pallor, fatigue, and anemia in four children aged 10 to 15 yr.

Other symptoms include intestinal obstruction and recurrent abdominal pain. At laparotomy, all patients are found to have segmental saccular or tubular dilatation of the terminal ileum. The dilated segments vary in length from 8 to 25 cm. Meckel’s diverticula is present in some patients.

Previous reports have referred to this abnormality as "giant Meckel’s diverticulum" or "segmental ileal dilatation."

Evaluation of patients suggests that this entity is an intrinsic abnormality of ileal development at the morphologically active site of juncture with the yolk stalk.

References

- Segmental dilatation of intestine: a case report and review of the literature. Balik E, Taneli C, Yazici M, Demircan M, Herek O. Eur J Pediatr Surg. 1993 Apr;3(2):118-20. PMID: #8323919#

- Ileal dysgenesis in infants and children. Bell MJ, Ternberg JL, Bower RJ. J Pediatr Surg. 1982 Aug;17(4):395-9. PMID: #7120007#