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rheumatoid aortitis

Wednesday 29 June 2011

Aortitis as a feature of rheumatoid arthritis is considered rare.

Synopsis

- aortitis
- involvement of the thoracic aorta, in most cases
- involvement of both the thoracic and abdominal aorta,
- possible aneurysmal dilatation of the thoracic aorta or the abdominal aorta

Microscopy

- aortitis
- necrosis of medial smooth muscle and elastica
- inflammatory infiltrate comprising primarily lymphocytes and plasma cells
- panmural aortitis
- rheumatoid granulomas

Complications

- congestive heart failure secondary to thoracic aortitis and aortic valvulitis
- rupture of an abdominal aortic aneurysm

References

- Rheumatoid aortitis: a rarely recognized but clinically significant entity. Gravallese EM, Corson JM, Coblyn JS, Pinkus GS, Weinblatt ME. Medicine (Baltimore). 1989 Mar;68(2):95-106. PMID: #2921941#