liposarcoma in uterine lipoleiomyoma
Wednesday 4 January 2012
Primary sarcomas of the uterus are uncommon, leiomyosarcoma being the most frequent. Most uterine sarcomas arise de novo, with malignant transformation of a benign mesenchymal tumor being a very rare event, and is reported only in leiomyomata.
Primary liposarcomas of the uterus are extremely rare and are most likely to arise from malignant transformation of a lipoleiomyoma.
These tumors should be added to the differential diagnosis of benign lipomatous tumors, myxoid mesenchymal tumors, and malignant mixed Müllerian tumors (if pleomorphic) of the uterus.
Liposarcoma arising in uterine lipoleiomyoma: a report of 3 cases and review of the literature. McDonald AG, Dal Cin P, Ganguly A, Campbell S, Imai Y, Rosenberg AE, Oliva E. Am J Surg Pathol. 2011 Feb;35(2):221-7. PMID: 21263242