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aggressive angiomyxoma

Wednesday 11 April 2012

AAM

Definition: Aggressive angiomyxoma is a large invasive vulvar lesion, with hypocellularity, bland stellate and spindle cells, prominent vessels and myxoid stroma.

Aggressive angiomyxoma is an invasive deep soft tissue lesion, most frequently found in the vulva; it is rarely found in the scrotum in men. It is commonly larger than 10 cm in greatest dimension, and is non-circumscribed. It is hypocellular, has bland stellate and spindle cells, prominent vessels and myxoid stroma. It is positive for desmin, vimentin, ER and PR.

Digital cases

- JRC:1443 : Aggressive angiomyxoma of pelvic soft tissues
- JRC:3175 : Aggressive angiomyxoma of pelvic soft tissues in a 40 y-o female.
- JRC:14570 : Aggressive angiomyxoma of the ischiorectal fossa.
- JRC:91 : Angiomyofibroblastoma or Aggressive angiomyxoma - rectovaginal septum.
- JRC:14781 : Aggressive angiomyxoma of the perirectal space.

Differential diagnosis

- myxoid leiomyoma
- myxoid neurofibroma
- myxolipoma
- intramuscular myxoma
- angiomyofibroblastoma

See also

- angiomyxomas

  • deep aggresive angiomyxoma