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pancreatic neuroendocrine tumors

Thursday 19 April 2012

pancreatic neuroendocrine tumor

Images

- neuroendocrine tumour of pancreas

Digital cases

- JRC:18768 : Pancreatic neuroendocrine tumor (Pancreas carcinoid-islet tumors)

Grading

Accurate grading w/Ki-67 index on FNA specimens using the WHO 2010/ENETS criteria.

See also

- neuroendocrine tumors
- pancreatic tumors

Open references

- Calculation of the Ki67 index in pancreatic neuroendocrine tumors: a comparative analysis of four counting methodologies. Reid MD, Bagci P, Ohike N, Saka B, Erbarut Seven I, Dursun N, Balci S, Gucer H, Jang KT, Tajiri T, Basturk O, Kong SY, Goodman M, Akkas G, Adsay V. Mod Pathol. 2015 May;28(5):686-94. doi : 10.1038/modpathol.2014.156 PMID: 25412850 (Free)

- Pancreatic neuroendocrine tumors: Accurate grading with Ki-67 index on fine-needle aspiration specimens using the WHO 2010/ENETS criteria. doi : 10.1002/cncy.21457

References

- Aberrant Menin expression is an early event in pancreatic neuroendocrine tumorigenesis. Hackeng WM, Brosens LA, Poruk KE, Noë M, Hosoda W, Poling JS, Rizzo A, Campbell-Thompson M, Atkinson MA, Konukiewitz B, Klöppel G, Heaphy CM, Meeker AK, Wood LD.
Hum Pathol. 2016 Jun 21. doi : 10.1016/j.humpath.2016.06 006
PMID: 27342911

- Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors. de Wilde RF, Heaphy CM, Maitra A, Meeker AK, Edil BH, Wolfgang CL, Ellison TA, Schulick RD, Molenaar IQ, Valk GD, Vriens MR, Borel Rinkes IH, Offerhaus GJ, Hruban RH, Matsukuma KE. Mod Pathol. 2012 May 11. PMID: 22575867