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atheroma

Wednesday 26 September 2012

WKP

Definition: In pathology, an atheroma (from ἀθήρωμα (athērōma), “tumor full gruel-like matter”) is an accumulation and swelling in artery walls made up of (mostly) macrophage cells, or debris, and containing lipids (cholesterol and fatty acids), calcium and a variable amount of fibrous connective tissue.

Atheroma causes atherosclerosis, which is one of the three subtypes of arteriosclerosis (which are atherosclerosis, Monckeberg’s arteriosclerosis and arteriolosclerosis).

Classification

- Type I: Isolated macrophage foam cells
- Type II: Multiple foam cell layers
- Type III: Preatheroma, intermediate lesion
- Type IV: Atheroma
- Type V: Fibroatheroma
- Type VI: Fissured, ulcerated, hemorrhagic, thrombotic lesion
- Type VII: Calcific lesion
- Type VIII: Fibrotic lesion