proliferative actinic keratosis
Friday 12 October 2012
In proliferative actinic keratosis, there is a strong propensity to transform into an invasive squamous cell carcinoma.
Nests of atypical cells extend as finger-like projections into the upper dermis.
It has a pseudo-infiltrative appearance.
Extension down hair follicles and, less frequently, acrosyringia may be present.
A heavy inflammatory cell infiltrate of lymphocytes and some plasma cells is often present