- Human pathology

Home > E. Pathology by systems > Skin > guttate


Friday 16 November 2012

In guttate lesions, the changes are more superficial with less collagen sclerosis but with subepidermal edema, resembling this feature of lichen sclerosus et atrophicus.

Linear lesions may show a deeper and more diffuse inflammatory cell infiltrate extending into the underlying muscle. Vascular changes are usually prominent.

Ossification of the dermis has been recorded.

The inflammation in the subcutis is also marked in the generalized form and in subcutaneous morphea; in both there may be marked fibrosis in the subcutis.