Friday 16 November 2012
In subcutaneous morphea, there is thickening and hyalinization of collagen in the deep dermis and in the septa and fascia.
There is a mixed inflammatory cell infiltrate which includes some multinucleate giant cells.
Lipomembranous (membranocystic) changes may be present.
Some confusion has arisen because of the variable use of the term ‘subcutaneous morphea’.
One group has suggested that the term ‘morphea profunda’ be used as an all-embracing one to include cases with dermal, subcutaneous and fascial involvement, while ‘subcutaneous morphea’ should be used for cases in which the subcutaneous fat is mainly affected.
According to this concept, "eosinophilic fasciitis" refers to the fascial component of morphea profunda.
The concept has not gained wide acceptance.