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solid pseudopapillary tumor of the pancreas with multinucleated giant tumor cells

Monday 17 December 2012

Solid pseudopapillary neoplasm of the pancreas with prominent atypical multinucleated giant tumour cells

Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low-grade malignant neoplasm. SPN with prominent atypical multinucleated giant tumour cells (MNGTCs) has been very rarely reported.

The presence of MNGTCs in SPN most probably represents degenerative change of the tumour cells and does not seem to affect the prognosis.

Reference

- Solid pseudopapillary neoplasm of the pancreas with prominent atypical multinucleated giant tumour cells. Li L, Othman M, Rashid A, Wang H, Li Z, Katz MH, Lee JE, Pisters PW, Abbruzzese JL, Fleming JB, Wang H. Histopathology. 2012 Sep 4. PMID: 23134473