Thursday 3 January 2013
Nodular lactational hyperplasia
Definition: Lactating adenoma is a focus of hyperplasia seen in breasts during pregnancy or puerperial period.
Lactating adenoma may be solitary or multiple and has a gray cut surface.
enlarged lobules containing markedly increased number of glands.
greatly expanded lobules consisting of variably-sized glands.
apical cytoplasmic blebs and fraying of the luminal border.
The lobules are lined by actively secreting epithelial cells with vacuolated cytoplasm.
Secretions may accumulate in the glands.
The cells have basophilic cytoplasm, hyperchromatic nuclei with prominent nucleoli, and inconspicuous myoepithelial cell layer.