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IgG4-associated pleural disease

Friday 4 January 2013

IgG4-related lung and pleural disease

Pleura is severely thickened by diffuse sclerosing inflammation.

Fibrosis is more pronounced on the side of the pleural cavity.

In the parietal lesion, sclerosing inflammation extends into subpleural fibrous and adipose tissue.

Visceral pleural lesions severely involve subpleural lung parenchyma.

Those parenchymal lesions resembled the solid nodular type.


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- IgG4-related lung and pleural disease: a clinicopathologic study of 21 cases. Zen Y, Inoue D, Kitao A, Onodera M, Abo H, Miyayama S, Gabata T, Matsui O, Nakanuma Y. Am J Surg Pathol. 2009 Dec;33(12):1886-93. doi: 10.1097/PAS.0b013e3181bd535b. PMID: #19898222#

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