Home > E. Pathology by systems > Respiratory system > Lungs > pulmonary mucinous cystadenocarcinoma

pulmonary mucinous cystadenocarcinoma

Friday 18 January 2013

Mucinous cystadenocarcinoma of the lung

Like the ovarian counterparts, this groups of tumors shows a histologic spectrum encompassing benign (mucinous cystadenoma), borderline (mucinous cystic tumor of borderline malignancy) and malignant (mucinous cystadenocarcinoma).

The cytological and architectural criteria for differentiating these tumors are also similar to those in the ovary, except that invasion of surrounding lung is diagnosed as a mixed subtype of adenocarcinoma (for reasons I’m not quite clear but there it is).

The mucinous epithelium in all of these cystic lesions differ from the mucinous adenocarcinoma type in that these express CK7 but inconsistently express CK20 and TTF-1. These are quite rare and have been studied for MUC2 or CDX2.

See also

- mucinous adenocarcinoma of the lung

Open references

- Cystic mucinous adenocarcinoma of the lung: a case report. Cabibi D, Sciuto A, Geraci G, Lo Nigro C, Modica G, Cajozzo M. J Cardiothorac Surg. 2011 Oct 4;6:128. doi: 10.1186/1749-8090-6-128 . PMID: #21970610# (free)