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vesical paraganglioma
Wednesday 26 June 2013
Bladder Paragangliomas
Molecular variants
Succinate Dehydrogenase-deficient Bladder Paragangliomas (23797725)
- A significant subset of bladder paragangliomas is SDH deficient.
- It is essential to identify SDH-deficient tumors, as the presence of an SDH mutation has prognostic implications and is important in guiding genetic counseling.
References
Identification of Succinate Dehydrogenase-deficient Bladder Paragangliomas. Mason EF, Sadow PM, Wagner AJ, Remillard SP, Flood TA, Belanger EC, Hornick JL, Barletta JA. Am J Surg Pathol. 2013 Jun 20. PMID: 23797725
