Wednesday 28 August 2013
Definition: Squamous metaplasia refers to benign non-cancerous change (metaplasia) of (non-squamous) surfacing lining cells (epithelium) to a squamous morphology.
Common sites for squamous metaplasia include the bladder and cervix. Smokers often exhibit squamous metaplasia in the linings of their airways. These changes don’t signify a specific disease, but rather usually represent the body’s response to stress or irritation. Vitamin A deficiency can lead to squamous metaplasia.
Squamous metaplasia may be seen in the context of benign lesions (e.g. atypical polypoid adenomyoma), chronic irritation or cancer (e.g. endometrioid endometrial carcinoma).
bronchial squamous metaplasia
cervical squamous metaplasia