- Human pathology

Home > A. Molecular pathology > PLS3


Sunday 5 January 2014


Definition: Plastin-3 is a highly-conserved protein that in humans is encoded by the PLS3 gene on the X chromosome.


- PLS3 variants

- Colorectal cancer

  • Aberrant Expression of Plastin-3 Via Copy Number Gain Induces the Epithelial-Mesenchymal Transition in Circulating Colorectal Cancer Cells. PMID: 24217791
  • Plastin polymorphisms predict gender and stage-specific colon cancer recurrence after adjuvant chemotherapy. PMID: 24170770
  • A common gene variant in PLS3 predicts colon cancer recurrence in women. PMID: 23549633
  • Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis. PMID: 23378342

- Sezary syndrome