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KIF5B

Sunday 5 January 2014

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Definition: Kinesin-1 heavy chain is a protein that in humans is encoded by the KIF5B gene. KIF5B has been shown to interact with SNAP-25, SNAP23, KLC2, YWHAH and KLC1.

Pathology

- KIF5B-RET fusion in lung adenocarcinoma (#23932363#)

References

- Diagnostic method for the detection of KIF5B-RET transformation in lung adenocarcinoma. Go H, Jung YJ, Kang HW, Park IK, Kang CH, Lee JW, Ju YS, Seo JS, Chung DH, Kim YT. Lung Cancer. 2013 Oct;82(1):44-50. doi:10.1016/j.lungcan.2013.07.009 . PMID: #23932363#

- KIF5B/RET fusion gene analysis in a selected series of cytological specimens of EGFR, KRAS and EML4-ALK wild-type adenocarcinomas of the lung. Borrelli N, Giannini R, Proietti A, Alì G, Pelliccioni S, Niccoli C, Lucchi M, Melfi F, Mussi A, Basolo F, Fontanini G. Lung Cancer. 2013 Sep;81(3):377-81. doi:10.1016/j.lungcan.2013.06.026 . PMID: #23891510#