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solitary fibrous tumor of soft tissues

Tuesday 24 June 2014

solitary fibrous tumour

Variants

- myxoid solitary fibrous tumor
- lipomatous solitary fibrous tumor

Immunochemistry

- CD99+, CD34+, BCL2+, STAT6+.

Molecular biology

- NAB2-STAT6 gene fusion

  • Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing. (23313952, 23313954)

See also

- thoracic solitary fibrous tumor
- solitary fibrous tumor of soft tissue

References

- Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors. Chmielecki J, Crago AM, Rosenberg M, O’Connor R, Walker SR, Ambrogio L, Auclair D, McKenna A, Heinrich MC, Frank DA, Meyerson M.
Nat Genet. 2013 Feb;45(2):131-2. doi : 10.1038/ng.2522 PMID: 23313954 [Free]

- Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing. Robinson DR, Wu YM, Kalyana-Sundaram S, Cao X, Lonigro RJ, Sung YS, Chen CL, Zhang L, Wang R, Su F, Iyer MK, Roychowdhury S, Siddiqui J, Pienta KJ, Kunju LP, Talpaz M, Mosquera JM, Singer S, Schuetze SM, Antonescu CR, Chinnaiyan AM. Nat Genet. 2013 Feb;45(2):180-5. doi : 10.1038/ng.2509 PMID: 23313952 [Free]