Interstitial fibroblastic foci
Wednesday 20 August 2014
Interstitial fibroblastic foci are circumscribed nodules of fibroblastic proliferation and immature connective tissue.
- Fibroblastic foci, consisting of proliferation of immature fibrous connective tissue at the periphery of an air space, are a characteristic finding in UIP and are indicative of disease activity.
- They may sometimes be found in other types of interstitial pneumonia.
- Temporal heterogeneity, patchy low power appearance and fibroblastic foci are important diagnostic features of UIP.