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tumor budding

Wednesday 25 February 2015

Definition: Tumor budding is a well-established adverse prognostic factor in colorectal cancer.

Images

- Recommendations for Reporting Tumor Budding in CRC based on the International Tumor Budding Consensus Conference 2016 at ESPIAP Cologne2016

By tumors

- tumor budding in colorectal carcinoma (CRC)

  • Tumor budding is a well-established adverse prognostic factor in colorectal cancer.

- pancreatic ductal adenocarcinoma

  • Tumor Budding Is an independent adverse prognostic factor in pancreatic ductal adenocarcinoma. (25634751)
  • The assessment of budding with H&E is reliable and could be used to better risk stratify patients with pancreatic ductal adenocarcinoma. (25634751)

- esophageal adenocarcinoma

  • Tumor budding is associated with an increased risk of lymph node metastasis and poor prognosis in superficial esophageal adenocarcinoma. (24762549)

Open references

- Tumor budding is associated with an increased risk of lymph node metastasis and poor prognosis in superficial esophageal adenocarcinoma. Landau MS, Hastings SM, Foxwell TJ, Luketich JD, Nason KS, Davison JM. Mod Pathol. 2014 Dec;27(12):1578-89. doi : 10.1038/modpathol.2014.66 PMID: 24762549 (Free)

References

- Tumor Budding Is an Independent Adverse Prognostic Factor in Pancreatic Ductal Adenocarcinoma. O’Connor K, Li-Chang HH, Kalloger SE, Peixoto RD, Webber DL, Owen DA, Driman DK, Kirsch R, Serra S, Scudamore CH, Renouf DJ, Schaeffer DF. Am J Surg Pathol. 2015 Jan 28. PMID: 25634751