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disease module - Humpath.com - Human pathology

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disease module

Saturday 10 October 2015

disease modularity

See also

- modularity

References

- A DIseAse MOdule Detection (DIAMOnD) algorithm derived from a systematic analysis of connectivity patterns of disease proteins in the human interactome. Ghiassian SD, Menche J, Barabási AL. PLoS Comput Biol. 2015 Apr 8;11(4):e1004120. doi : 10.1371/journal.pcbi.1004120 eCollection 2015 Apr. PMID: 25853560

- Disease networks. Uncovering disease-disease relationships through the incomplete interactome. Menche J, Sharma A, Kitsak M, Ghiassian SD, Vidal M, Loscalzo J, Barabási AL. Science. 2015 Feb 20;347(6224):1257601. doi : -10.1126/science.1257601 PMID: 25700523

- A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma. Sharma A, Menche J, Huang CC, Ort T, Zhou X, Kitsak M, Sahni N, Thibault D, Voung L, Guo F, Ghiassian SD, Gulbahce N, Baribaud F, Tocker J, Dobrin R, Barnathan E, Liu H, Panettieri RA Jr, Tantisira KG, Qiu W, Raby BA, Silverman EK, Vidal M, Weiss ST, Barabási AL. Hum Mol Genet. 2015 Jun 1;24(11):3005-20. doi : 10.1093/hmg/ddv001 PMID: 25586491