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foamy macrophages in thyroid FNA

Wednesday 27 April 2016

Etiology

- Amiodarone-induced change in thyroid

- hypercholesterolaemia due to hypothyroidism
- thyroid palpation-induced changes
- tumoral stoma of papillary thyroid carcinoma (PTC)

  • Foamy macrophages only without thyroglobulin level information in FNAC could raise the possibility of cystic metastatic papillary thyroid carcinoma (PTC) even if no identifiable tumor cells are found.
  • Foamy cells can be found in the stroma of papillary thyroid carcinoma (PTC).

See also

- amiodarone
- foamy macrophages in thyroid

References

- Importance of foamy macrophages only in fine needle aspirates to cytologic diagnostic accuracy of cystic metastatic papillary thyroid carcinoma. Koo JS, Kwak JY, Jung W, Hong S. Acta Cytol. 2010 May-Jun;54(3):249-54. PMID: 20518406