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adenomyoepithelial adenosis

Tuesday 2 May 2017

apocrine adenosis; secretory adenosis

PO

Definition: Uncommon variant of adenosis with proliferation of epithelial and myoepithelial cells. Adenomyoepithelial adenosis has prominent myoepithelial cells in 1-3 layers

Myoepithelial cells are widely present in the breast, and their hyperplasia may result in a spectrum of disease ranging from myoepitheliosis to myoepithelial carcinoma.

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Although considered benign, adenomyoepithelial lesions tend to recur due to inadequate excision. Therefore, possibility of recurrence and even metastasis should be considered during follow-up of patients with a diagnosis of adenomyoepithelial lesions.

Open references

- Adenomyoepithelial Adenosis of the Breast: Clinical, Radiological, and Pathological Findings for Differential Diagnosis.
Erel S, Tuncbilek I, Kismet K, Kilicoglu B, Ozer E, Akkus MA.
Breast Care (Basel). 2008;3(6):427-430. Epub 2008 Nov 25.
PMID: 21048915 Free