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poorly cohesive cell carcinoma of the gallbladder

Friday 30 September 2016

Poorly cohesive cell (diffuse-infiltrative/signet-ring cell) carcinomas of the gallbladder

Definition: Signet-ring cell carcinoma is an extremely rare type of gallbladder carcinoma.

Images

- Poorly cohesive cell (diffuse-infiltrative/signet-ring cell) carcinomas of the gallbladder

In the gastrointestinal system, carcinomas with single-cell or cord-like infiltration, previously called “diffuse-infiltrative” type or “signet-ring cell”, are now designated as “poorly cohesive cell” (PCC) type (regardless of with/without signet-ring cells) in the WHO-2010 classification.

PCC carcinoma originating in the gallbladder should be kept in mind for the differential diagnosis of disseminated poorly differentiated carcinomas in the abdomen.

Open references

- Primary signet ring cell carcinoma of gall bladder: report of an extremely rare histological type of primary gall bladder carcinoma. Ahmad Z, Qureshi A. BMJ Case Rep. 2010 Sep 7;2010.
doi : 10.1136/bcr.04.2009.1782
PMID: 22778190