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eyeliner sign

Wednesday 27 December 2017

Definition: “Eyeliner sign” is seen in squamous cell carcinoma in situ. Atypical keratinocytes fill epidermis but spare basal layer (line of normal basal keratinocytes under the atypical ones resembles eyeliner 👁).

Melanoma in situ does not have this pattern.

Images

- “Eyeliner sign” is seen in squamous cell carcinoma in situ.