low-grade cribriform cystadenocarcinoma
Wednesday 11 January 2017
Definition: Low-grade cribriform cystadenocarcinoma (LGCCC) is a recently described rare tumor of salivary gland which exhibits clinically indolent behavior.
This tumor predominantly consists of intraductal components and frequently exhibits papillary-cystic or cribriform proliferation pattern.
Immunohistochemically, the luminal tumor cells show diffuse expression of CK and S100.
Considering the histological features of LGCCC, it should be distinguished with :
papillocystic variant of acinic cell carcinoma ,
conventional salivary duct carcinoma ,
polymorphous low-grade adenocarcinoma,
carcinoma ex pleomorphic adenoma
mammary analogue secretory carcinoma MASC).
Low-grade cribriform cystadenocarcinoma of salivary glands: report of two cases. 2013. doi : 10.1186/1746-1596-8-28