Humpath.com - Human pathology

Home > A. Molecular pathology > immunoglobulin light chains

immunoglobulin light chains

Friday 12 December 2003

Pathology

- light-chain–deposition disease

Pathogeny

- Local microenvironmental conditions affect the ultrastructural organization of protein deposits. For example, pH influences the processing of immunoglobulin light chains, causing them to form either fibrillar amyloid aggregates or amorphous aggregates characteristic of light-chain–deposition disease.