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DUSP22 - Humpath.com - Human pathology

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DUSP22

HGNC:16077 6p25.3

Monday 6 March 2017

Dual specificity protein phosphatase 22

WKP

Definition: Dual specificity protein phosphatase 22 is an enzyme that in humans is encoded by the DUSP22 gene.

Interactions

DUSP22 has been shown to interact with MAPK1 and MAPK8.

Pathology

- Indolent ALK-Negative Anaplastic Large Cell Lymphoma (ALCL) with DUSP22 Rearrangement (28042680)

- primary cutaneous Anaplastic Large Cell Lymphoma (ALCL) with DUSP22 Rearrangement (28042680)

See also

- IRF4

  • IRF4-rearranged ALCL

Open references

- Morphologic Features of ALK-negative Anaplastic Large Cell Lymphomas With DUSP22 Rearrangements. King RL, Dao LN, McPhail ED, Jaffe ES, Said J, Swerdlow SH, Sattler CA, Ketterling RP, Sidhu JS, Hsi ED, Karikehalli S, Jiang L, Gibson SE, Ondrejka SL, Nicolae A, Macon WR, Dasari S, Parrilla Castellar E, Feldman AL. Am J Surg Pathol. 2016 Jan;40(1):36-43. doi : 10.1097/PAS.0000000000000500
PMID: 26379151 Free