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CMV-associated inflammatory pseudotumor - Humpath.com - Human pathology

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CMV-associated inflammatory pseudotumor

Wednesday 15 March 2017

Cytomegalovirus pseudotumor

Cytomegalovirus (CMV) is a common pathogen affecting the gastrointestinal tract in patients with AIDS.

CMV-induced pseudotumor in patients with AIDS is an exceptionally rare clinical entity.

CMV pseudotumor should be included in the differential diagnosis of gastrointestinal mass lesions in AIDS patients and in other immunocompromised patients.

The tumor often responds to antiviral therapy, but resolution of a CMV mass as a result of oral antiviral therapy has not been previously described.

Since pseudotumors secondary to CMV often respond to medical treatment, it is important that the physicians treating severely immunocompromised patients are aware of this entity.

Localization

- duodenum

  • CMV-induced pseudotumor has been described in duodenum in patients with AIDS

Open references

- Cytomegalovirus pseudotumor of the duodenum in a patient with AIDS: an unrecognized and potentially treatable clinical entity.
Kelesidis T, Tozzi S, Mitty R, Worthington M, Fleisher J.
Int J Infect Dis. 2010 Apr;14(4):e274-82. doi : 10.1016/j.ijid.2009.04.015. Review
PMID: 19695917