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Mycobacterium chimaera

Friday 26 October 2018

Mycobacterium chimaera was identified as a species within the Mycobacterium avium complex in 2004. Until recently, it was predominantly seen in immunocompromised patients. In 2015, an outbreak of disseminated M. chimaera disease was described in European patients after undergoing open-heart surgery in which contaminated heater-cooler water units were used.

Mycobacterium chimaera hepatitis, the sinusoidal location of the granulomas contributes to the venous obstructive changes. Recognition of this characteristic dual pattern of injury can allow pathologists to suggest the diagnosis and prompt the appropriate diagnostic and therapeutic interventions.

Paywall references

- Mycobacterium chimaera Hepatitis: A New Disease Entity. Shafizadeh N, Hale G, Bhatnagar J, Alshak NS, Nomura J. Am J Surg Pathol. 2018 Oct 20. doi : 10.1097/PAS.0000000000001179 PMID: 30346305