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mast cells

Saturday 29 December 2018

mastocyte

WKP

Definition : A mast cell (also known as a mastocyte or formerly a labrocyte) is a type of white blood cell. Specifically, it is a type of granulocyte derived from the myeloid stem cell that is a part of the immune and neuroimmune systems and contains many granules rich in histamine and heparin.

Although best known for their role in allergy and anaphylaxis, mast cells play an important protective role as well, being intimately involved in wound healing, angiogenesis, immune tolerance, defense against pathogens, and blood–brain barrier function.

Pathology : Pathology of mast cells

- role in allergic disease and anaphylaxis
- mastocytosis / mastocytoses