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enteritis cystica profunda

Saturday 12 January 2019

In enteritis cystica profunda, the mucin-filled cysts in the bowel wall outside of the mucosal layer are thought to arise after mucosal ulceration or inflammatory damage to the submucosa has allowed outgrowth of epithelial elements into the other layers of the bowel wall.

These ectopic epithelial elements frequently lack a continuous epithelial lining and are usually surrounded by an inflammatory cell infiltrate. Other features can include calcifications, fibrosis and ossified deposits within the mucin lakes.

Enteritis cystica profunda is a benign entity and similar changes can be found anywhere along the gastrointestinal tract.

In the colon it can mimic invasive adenocarcinoma, especially when the ectopic mucosal elements occur within large dysplastic sigmoid colon adenomas.

Open references

- Enteritis cystica profunda. 2004 JRSM

See also

- gastritis cystica profunda
- colitis cystica profunda