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melanotic paraganglioma

Tuesday 22 January 2019

Pigmented Pheochromocytoma

Definition : Pigmental paraganglioma is a special and rare type of paraganglioma. It featured multiple pigment particles in the cytoplasm. Paragangliomas are rare neoplasms arising from undifferentiated cells of the primitive neural crest.

Pigmented paraganglioma has been reported across a wide age range (17-57 years), and no gender differences were noted. It has arisen in the bladder, posterior peritoneum, mediastinum, spine, and other sites.

Open references

- Primary Melanotic Paraganglioma of Thyroid Gland: Report of a Rare Case With Clinicopathologic and Immunohistochemical Analysis and a Literature Review. 2017

- Pigmented paraganglioma of the kidney: a case report. Zhao L, Luo J, Zhang H, Da J. Diagn Pathol. 2012 Jun 28;7:77. doi : 10.1186/1746-1596-7-77 PMID: 22741527

Paywall references

- Pigmented Pheochromocytoma: an Unusual Variant of a Common Tumor. Kakkar A, Kaur K, Kumar T, Cherian LB, Kaushal R, Sharma MC, Dhar A, Seth A, Jain D. Endocr Pathol. 2016 Mar;27(1):42-5. doi : 10.1007/s12022-015-9407-2 PMID: 26578456