Humpath.com - Human pathology

Home > G. Tumoral pathology > angiomyxomas

angiomyxomas

Thursday 29 January 2004

Digital case

- JRC:1443 : Aggresive angiomyxoma of pelvic soft tissues
- JRC:15102 : Vulvar angiomyxoma, angiomyofibroblastoma variant.

Definition: Angiomyxoma is a myxoid myofibroblastic tumor.

Types

- superfical angiomyxoma (cutaneous myxoma)
- deep angiomyxoma

Variants

- aggressive angiomyxoma (AA) (14608546)

Localization

- vulva
- vagina
- hypodermis
- larynx (8868184)

Cytogenetics

- chromosomal translocation t(8;12) induces aberrant HMGIC expression in aggressive angiomyxoma of the vulva (11550285)
- 12q13-15 rearrangement with HMGA2 abnormal expression