Humpath.com - Human pathology

Home > E. Pathology by systems > Skin > digital papillary adenocarcinoma

digital papillary adenocarcinoma

Friday 20 September 2019

Aggressive digital papillary adenocarcinoma

Definition : Aggressive digital papillary adenocarcinomas are rare malignant tumors often located on the digits of the hand. Due to lack of pain, slow growth, and an inconspicuous appearance, diagnosis is often missed or delayed.

Digital papillary carcinoma (DPC) is a rare, slow growing, malignant tumor with eccrine differentiation that occurs predominantly in digits. This tumor was originally classified as a benign neoplasm; aggressive digital papillary adenoma (ADPA) was first described by Helwig in 1979. In 1987, Kao et al. classified ADPA and aggressive digital papillary adenocarcinoma (ADPAca) based on differences in histologic findings.

Etiopathogeny

- HPV42

Open references

- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386778/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284491/