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nodular hidradenoma

Friday 28 August 2020

hidradenoma, eccrine acrospiroma

PO

Synopsis

- nests / lobules of cells resembling eccrine poroma with either clear cytoplasm or prominent squamous metaplasia
- possible marked vascularity
- small and large lumina are lined by cuboidal ductal cells or columnar secretory cells
- cystic spaces may be due to degeneration of tumor cells

Images

- https://twitter.com/SkinPathology/status/638584069907857409
- https://twitter.com/TexPathol/status/1038034487647633408

Differential diagnosis

- apocrine mixed tumor
- glomus tumor (different staining pattern)
- cutaneous metastasis / metastatic disease ( clear cell renal cell carcinoma )
- primary skin tumors with follicular differentiation
- tumors with sebaceous differentiation
- tumors with sweat gland differentiation