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Wednesday 28 October 2020

Definition : Serine/threonine-protein kinase Ds are enzymes that in humans is encoded by the PRKDs genes.

Members of the protein kinase D ( PKDs ) family function in many extracellular receptor-mediated signal transduction pathways.


- polymorphous adenocarcinoma of the salivary gland harbor genetic alterations affecting PRKD genes. PMID: 31492931

- The PRKD1 E710D hotspot mutation is highly specific in separating polymorphous adenocarcinoma of the palate from adenoid cystic carcinoma and pleomorphic adenoma on FNA. PMID: 29266837