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Myocarditis Associated With Immune Checkpoint Inhibitor Therapy

Wednesday 28 October 2020

Myocarditis Associated With Immune Checkpoint Inhibitor Therapy

Synopsis

- significant and prominent interstitial inflammatory infiltrate composed of numerous histiocytes with interspersed lymphocytes.
- This lymphohistiocytic infiltrate was associated with evidence of myocardial injury.

  • This included loss of myocyte nuclei, myocytes with irregular cell membranes with moth-eaten appearance, hypereosinophilia, and shrunken and irregular cardiac myocytes, but not associated with fibrosis .

Open references

- https://meridian.allenpress.com/aplm/article/144/11/1392/442293/Histopathologic-Characterization-of-Myocarditis